Dementia Discovery Group

The research in our group focusses on understanding the early cell biological processes that drive Alzheimer’s Disease and other related dementias. We use human stem cell-derived neurons, astrocytes and microglia combined with CRISPR-Cas9 gene-editing to understand how genetic factors drive the earliest stages of disease pathogenesis. We use this knowledge to develop novel drugs for these disorders, with a strong focus on lipid metabolism. - more info coming soon

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