The Dutch Research Council (NWO) has awarded an ENW-M2 open competition grant of 730 k€ to CNCR researcher Wiep Scheper (PI team) to study the role of de-ubiquitinating enzymes in tau-induced dysfunction of the neuronal auto- and endo-lysosomal system. In this multidisciplinary project Scheper PI of the Molecular Neurodegeneration group teams up with ubiquitin signalling expert Aysegul Sapmaz (LUMC, Leiden).

Max will start at FGA on March 1st, building a team aimed at understanding the molecular mechanisms and functional relevance of mRNA trafficking and local translation in neuronal subcellular compartments in health and disease.

Irune Guerra San Juan and Matthijs Verhage (FGA) became partners in an international consortium that designs and tests oligonucleotides to suppress poison exon insertion and restore full length Stathmin 2 expression in sporadic ALS

Van der Kant and the VU Medical Center receive funding for unravelling the associative link between exercise and lipid metabolism in prevention against Alzheimer.

In a study published in Molecular Psychiatry, Jessie Brunner, Hanna Lammertse and Annemiek van Berkel (FGA) teamed up with Sophie van der Sluis (CTG) and the proteomics facility (MCN) to optimize statistical power for iPSC-based study designs.

Amelie Freal, head of the team, joined CNCR earlier this year and is developing an independent research program on axon initial segment biology at FGA.

The PreSSAD consortium of 6 EU partners incl. CNCR (Matthijs Verhage, FGA) was awarded (JPND/Memorabel, pre-diagnosis disturbances in neurodevelopmental disorders) and will start Nov 1st with IPSC-based models of presynaptic degeneration

The performance of CNCR researchers Rachel Brouwer, Loek van der Kallen and Mahesh Karnani has been evaluated positively and we are happy to announce that they are rewarded a permanent employment contract.

Rik van der Kant, Natalia Goriounova and Priyanka Rao-Ruiz, researchers at the Center for Neurogenomics & Cognitive Research at the Vrije Universiteit Amsterdam, have been awarded by the Dutch Research Council (NWO) with a Vidi grant worth 800,000 euros.

A new study by Kim Wolzak and colleagues from the team of Wiep Scheper reveals how neurons shift their translational control to ensure proteostatic resilience during ER stress. The study was published in The EMBO Journal.