Claudia Persoon (CNCR-FGA) and colleagues identified RAB3 and RIM1/2 as essential factors for neuromodulator secretion from dense core vesicles in mammalian neurons. This study is now published in Neuron.
CNCR organized, together with new UMCA professor Hilgo Bruining, a colloquium at the Royal Academy bringing together world leaders to discuss neurodevelopmental disorders and science-based intervention for individual patients.
A study performed by PhD student Vera Wiersma (FGA), from the team of Wiep Scheper, and colleagues reveals that neurons develop granulovacuolar degeneration bodies in response to tau pathology. This collaborative effort was published in Acta Neuropathologica.
In this study Marinka Brouwer (FGA) shows that adhesion molecule SALM1 binds an intracellular protein complex via one domain and organizes synapse development via another. The study was a collaboration between FGA and MCN.
Femke Feringa (FGA) did her PhD in cancer research but decided to switch to neurodegeneration and study why genes involved in immune responses and cholesterol metabolism are among the strongest associations with Alzheimer’s disease.
Wijnand Geraerts, biologist by training, designed CNCR together with Menno Witter and Dorret Boomsma, promoting groundbreaking, multidisciplinary research and bringing scientists with different backgrounds together within CNCR.
Ricarda Weiland and Maaike van Boven received a prize for best poster at the Dutch Neuroscience Meeting 2019. In their winning poster they presented their first results in the BECAUSE project, in which they investigate mechanisms involved in sensory sensitivity in people with autism.