A study by Enqi He (CNCR-FGA) published in Nature Communications demonstrates how synaptic vesicles remain in a high-energy (‘primed’) state, ready to be released. Two proteins, Munc13-1 and Munc18-1, stabilize the primed state by preventing de-priming and hereby support high frequency synaptic transmission.
Margherita Farina will defend her thesis ‘Trafficking and secretion of neuropeptides in mouse hippocampal neurons’. Related to this event, the German expert on BDNF signalling, Prof. V. Lessmann, will present a lecture “Postsynaptic BDNF secretion and action in spike timing-dependent LTP“ on Wed, June28th 3PM @W&N F123
Javier Emperador-Melero, PhD-student at FGA, describes how regulated secretory pathways mature in mixed excitatory/inhibitory micro-networks of human iPS-cell derived neurons