Javier Emperador-Melero, PhD-student at FGA, describes how regulated secretory pathways mature in mixed excitatory/inhibitory micro-networks of human iPS-cell derived neurons
Arthur de Jong and Matthijs Verhage publish a study on how adjustments of synaptic strength depend on the phosphorylation of Synaptotagmin-1, the major calcium-sensor for transmitter release.
Epileptic seizures arise when the activity of the brain gets out of control. A large research team at CNCR has investigated how the brain controls its activity and identified a new molecular pathway involving the synaptic protein Munc18-1 that helps the brain to slow down when activity gets too high. The study appeared in EMBO Journal.