Dr. Rik van der Kant (CNCR-FGA) and colleagues report that accumulation of cholesterol in Alzheimer’s disease neurons drives early Tau- and Amyloid pathology, and can be reversed by cholesterol-targeting drugs. Published in Cell Stem Cell.
On Saturday the 13th of October the first group of STXBP1-E families came to the VUmc to participate in the new study on STXBP1-Encephalopathy.
Claudia Persoon (CNCR-FGA) & the DCV team published a study on how many secretory vesicles are found in different CNS neurons (this paper is about vesicle pools, not swimming pools!) and how many vesicles fuse upon stimulation. The paper is featured on the cover of EMBO J. this month.